abstract：:Chronic hand eczema (CHE) is a debilitating and distressing disease for patients, the physical symptoms of which are compounded by psychosocial problems. Alitretinoin is an endogenously occurring physiological vitamin A derivative (retinoid) that possesses strong anti-inflammatory and immunomodulatory activity. It is ...

journal_title：Clinical and experimental dermatology

authors： English J,Graham-Brown R,de Sica Chapman A,Alexandroff AB

更新日期：2011-03-01 00:00:00

abstract：BACKGROUND:The various clinical types of lupus erythematosus (LE) show an essentially similar histological picture, and the subsets of LE cannot easily be distinguished by histology alone. However, there is an important clinical difference: lesions of discoid LE (DLE) cause scarring, particularly on the scalp, whereas ...

journal_title：Clinical and experimental dermatology

authors： Al-Refu K,Goodfield M

更新日期：2011-01-01 00:00:00

abstract：:Systemic sclerosis (SSc) is often complicated by severe skin ulcers that are unresponsive to traditional treatments. Vascular alterations are responsible for the ischaemic features of the disease in both the skin and visceral organs. Defective neoangiogenesis correlates with an abnormally reduced quantity of circulati...

journal_title：Clinical and experimental dermatology

authors： Ferri C,Giuggioli D,Manfredi A,Quirici N,Scavullo C,Colaci M,Gianelli U,Deliliers GL,Del Papa N

更新日期：2010-12-01 00:00:00

abstract：BACKGROUND:Drug-induced hypersensitivity syndrome (DIHS)/drug rash with eosinophilia and systemic symptoms (DRESS) syndrome is characterized by late disease onset, fever, rash, hepatic dysfunction, haematological abnormalities, lymphadenopathy and often, human herpesvirus (HHV) reactivation. The diagnosis of DIHS is ba...

journal_title：Clinical and experimental dermatology

authors： Teraki Y,Shibuya M,Izaki S

更新日期：2010-10-01 00:00:00

abstract：BACKGROUND:Epidermal replacement is an important step in the management of patients with post-traumatic and iatrogenic scars. Skin-colour variation from disease or trauma causes significant changes in self-image and appearance. AIM:The aim of our study was to analyse the results obtained with a novel autologous cell-h...

journal_title：Clinical and experimental dermatology

authors： Cervelli V,De Angelis B,Spallone D,Lucarini L,Arpino A,Balzani A

更新日期：2010-10-01 00:00:00

abstract：BACKGROUND:Malignant melanoma (MM), accounts for around 10% of skin cancers. To date, there have been few data on patient satisfaction with initial management of MM. OBJECTIVE:To identify the predictors of patient satisfaction with initial diagnosis and management of MM. METHODS:Data on 214 patients were collected us...

journal_title：Clinical and experimental dermatology

authors： Sheth N,Sarker SJ,Harries M,Healy C,Russell-Jones R,Acland K

更新日期：2010-08-01 00:00:00

abstract：BACKGROUND:Immune reconstitution inflammatory syndrome (IRIS) occurs in 10-25% of unselected patients starting highly active antiretroviral therapy (HAART). About 52-78% of these cases involve cutaneous features. AIM:To describe the prevalence and incidence of new dermatological conditions within 6 months of patients ...

journal_title：Clinical and experimental dermatology

authors： Osei-Sekyere B,Karstaedt AS

更新日期：2010-07-01 00:00:00

abstract：:Summary Mid-dermal elastolysis is an unusual process characterized by the absence of the elastic fibres within the mid-dermis. The disappearance of these fibres causes fine wrinkles (type 1) or perifollicular protrusions (type 2) affecting the trunk, neck and arms. There is a female predilection, and most patients hav...

journal_title：Clinical and experimental dermatology

authors： Cutillas E,Ferrando FJ,Martí ME,Mateu A,Rausell N

更新日期：2010-07-01 00:00:00

abstract：BACKGROUND:Alopecia areata (AA) is an organ-specific autoimmune disease characterized by folliculotropic T-cell infiltrates around anagen-stage hair follicles. The role of T helper (Th)1 and Th2 cytokines in the pathogenesis of AA have not been established. AIM:To determine whether serum cytokine profiles define the s...

journal_title：Clinical and experimental dermatology

authors： Barahmani N,Lopez A,Babu D,Hernandez M,Donley SE,Duvic M

更新日期：2010-06-01 00:00:00

abstract：:We describe the challenging case of a patient presenting with extensive, eruptive mid-facial squamous cell carcinomas (SCCs) and keratoacanthomas (KAs) consequent to radiotherapy. Our patient had a personal and family history of multiple KAs and SCCs. Multiple self-healing squamous epithelioma, otherwise known as Ferg...

journal_title：Clinical and experimental dermatology

authors： Robertson SJ,Bashir SJ,Pichert G,Robson A,Whittaker S

更新日期：2010-06-01 00:00:00

abstract：:A lighter or whiter complexion is socially desirable in many cultures. This has led to an unregulated and highly profitable market in skin-lightening creams that are readily available over the counter or on the internet. Plant extracts and newer tyrosinase inhibitors such as kojic acid or its derivative kojic dipalmit...

journal_title：Clinical and experimental dermatology

authors： Madhogaria S,Ahmed I

更新日期：2010-06-01 00:00:00

abstract：:Melkersson-Rosenthal syndrome (MRS) is an uncommon, complex neuromucocutaneous disorder characterized by recurrent orofacial oedema, facial palsy and fissured tongue. Complete MRS is uncommon. A case of complete MRS with multiple cranial nerve palsies is reported. ...

journal_title：Clinical and experimental dermatology

authors： Zeng W,Geng S,Niu X,Yuan J

更新日期：2010-04-01 00:00:00

abstract：BACKGROUND:Topical tacrolimus has shown remarkable clinical efficacy in treating many dermatoses. Combining ultraviolet (UV) B and tacrolimus is an intriguing therapeutic regimen, especially for treatment of vitiligo, for which combination therapy may show greater clinical efficacy than topical tacrolimus alone. The ph...

journal_title：Clinical and experimental dermatology

authors： Lan CC,Yu HS,Huang SM,Wu CS,Kuo HY,Lee CH,Lin CS,Chen GS

更新日期：2010-03-01 00:00:00

abstract：:Vitiligo is a disease characterized by the loss of melanocytes, resulting in progressive depigmentation of skin, and areas of normally pigmented skin can be of cosmetic concern. Several options have been tried to remove the pigment and make the skin a more even colour. We present an easy and effective therapeutic proc...

journal_title：Clinical and experimental dermatology

authors： Di Nuzzo S,Masotti A

更新日期：2010-03-01 00:00:00

abstract：BACKGROUND:Port-wine stains (PWS) are congenital capillary malformations that persist throughout life. Laser therapy is a common treatment for PWS, and pulsed-dye laser is the current treatment of choice. AIM:To compare the clinical results on untreated PWS of two dye lasers with different wavelengths and pulse durati...

journal_title：Clinical and experimental dermatology

authors： Frohm Nilsson M,Passian S,Wiegleb Edstrom D

更新日期：2010-03-01 00:00:00

abstract：:Acquired reactive perforating collagenosis (ARPC) is an uncommon dermatosis characterized by transepidermal elimination of altered collagen. It is commonly seen in patients with diabetes mellitus and/or chronic renal insufficiency. Rarely, it has been reported in association with malignancy and other conditions. We re...

journal_title：Clinical and experimental dermatology

authors： Yazdi S,Saadat P,Young S,Hamidi R,Vadmal MS

更新日期：2010-03-01 00:00:00

abstract：BACKGROUND:Atopic eczema (AE) is characterized by reduced skin hydration (SH) and impaired integrity of the skin. Proper emollient usage is an important facet of AE management and patients are encouraged to use emollients liberally. AIM:To evaluate whether the amount of emollient and skin cleanser used correlates with...

journal_title：Clinical and experimental dermatology

authors： Hon KL,Ching GK,Leung TF,Choi CY,Lee KK,Ng PC

更新日期：2010-01-01 00:00:00

abstract：:Malignant eccrine spiradenoma (MES) is an extremely rare cutaneous malignant tumour. An 86-year-old man presented at our hospital with an enlarging tumour on the dorsum of the left hand. An excisional biopsy was taken and histological examination showed a solid island of cells of two distinct types: cells with abundan...

journal_title：Clinical and experimental dermatology

authors： Tanese K,Sato T,Ishiko A

更新日期：2010-01-01 00:00:00

abstract：:We describe an 18-year-old girl with systemic lupus erythematosus (SLE) who had cutaneous papulonodular mucinosis (PNM) as the first sign of SLE. She presented with multiple flesh-coloured papules on the face, abdomen and limbs. Histological examination of a biopsy taken from a papule showed diffuse deposition of muci...

journal_title：Clinical and experimental dermatology

authors： Shekari AM,Ghiasi M,Ghasemi E,Kani ZA

更新日期：2009-12-01 00:00:00

abstract：:We report a 73-year-old man who developed repeated episodes of erythematous, bullous plaques beginning 3 months after discontinuation of combination treatment with pegylated interferon (IFN)-alpha-2b and ribavirin for hepatitis C virus infection. The first episode resolved within a week without treatment, but the lesi...

journal_title：Clinical and experimental dermatology

authors： Sato M,Sueki H,Iijima M

更新日期：2009-12-01 00:00:00

abstract：:Idiopathic solar urticaria (SU) is a rare, debilitating photodermatosis, which may be difficult to treat. First-line treatment with antihistamines is effective in mild cases, but remission after phototherapeutic induction of tolerance is often short-lived. Other treatment options include plasma exchange, photopheresis...

journal_title：Clinical and experimental dermatology

authors： Hughes R,Cusack C,Murphy GM,Kirby B

更新日期：2009-12-01 00:00:00

abstract：:We report a 29-year-old white woman who presented with oral involvement and subsequently developed severe and extensive laryngeal involvement with mucous membrane pemphigoid. She could not tolerate systemic corticosteroids due to side-effects. Dapsone improved only the oral disease, but the laryngeal disease remained ...

journal_title：Clinical and experimental dermatology

authors： Gürcan HM,Ahmed AR

更新日期：2009-12-01 00:00:00

abstract：:Acute generalized exanthematous pustulosis (AGEP) is an uncommon disease, which presents as a nonfollicular erythematous sterile pustular eruption. More than 90% of the cases are induced by adverse drug reactions, often triggered by anti-infectious systemic drugs. We report a case of itraconazole-induced AGEP in a 22-...

journal_title：Clinical and experimental dermatology

authors： Cançado GG,Fujiwara RT,Freitas PA,Correa-Oliveira R,Bethony JM

更新日期：2009-12-01 00:00:00

abstract：:Endogenous ochronosis or alkaptonuria is a rare, autosomal recessive disease of tyrosine metabolism that is caused by a deficiency of the enzyme homogentisic acid oxidase. The disease results in the accumulation and deposition of homogentisic acid in the cartilage, eyelids, forehead, cheeks, axillae, genital region, b...

journal_title：Clinical and experimental dermatology

authors： Turgay E,Canat D,Gurel MS,Yuksel T,Baran MF,Demirkesen C

更新日期：2009-12-01 00:00:00

abstract：:We report a case of the rare porokeratosis variant porokeratosis ptychotropica (PP). A circumferential perianal plaque and the characteristic histology of multiple cornoid lamellae with underlying dermal amyloid deposition were seen. Amyloid deposition was seen in the biopsied intertriginous area of the plaque only, w...

journal_title：Clinical and experimental dermatology

authors： Tallon B,Blumental G,Bhawan J

更新日期：2009-12-01 00:00:00

abstract：:We report a case of localized bullous pemphigoid (BP) in a woman patient with primary lymphoedema tarda. There is only one previous case reported of localized pemphigoid in an area of lymphoedema, this being of the cicatricial variant. Slow circulation in the lymphatic vessels, increased capillary permeability with pr...

journal_title：Clinical and experimental dermatology

authors： Perez A,Clements SE,Benton E,Robson A,Bhogal B,Stefanato CM,McGibbon D

更新日期：2009-12-01 00:00:00

abstract：:Piloleiomyoma is a benign tumour originating in the smooth muscles of the arrector pili muscle in the skin. The lesions are often sensitive to touch, cold and emotional disturbance. We present a patient with multiple piloleiomyoma (MPL) of the submentum who underwent reconstructive surgery using a submental perforator...

journal_title：Clinical and experimental dermatology

authors： Matsushita S,Ishihara T,Takeda K,Uchida Y,Tamai M,Usuki K,Kanekura T

更新日期：2009-12-01 00:00:00

abstract：:Angiolymphoid hyperplasia with eosinophilia (AHE) is a benign reactive vascular lesion characterized by a proliferation of small to medium sized vascular structures lined by epithelioid endothelial cells. We report a 75-year-old woman with a 1-month history of a painful ulcer on the tongue. Histopathological findings ...

journal_title：Clinical and experimental dermatology

authors： Garrido-Ríos AA,Sanz-Muñoz C,Torrero-Antón MV,Martínez-García G,Miranda-Romero A

更新日期：2009-12-01 00:00:00

abstract：BACKGROUND:In patients with psoriasis, videocapillaroscopy has been used to visualize the typical modifications in the microcirculatory architecture. AIM:To evaluate the modifications of the superficial capillary bed in a psoriatic plaque and healthy perilesional skin during treatment with a topical steroid. METHODS:...

journal_title：Clinical and experimental dermatology

authors： Stinco G,Lautieri S,Piccirillo F,Valent F,Patrone P

更新日期：2009-12-01 00:00:00

abstract：:Although Q-switched (QS) lasers are the mainstay of modern tattoo removal, paradoxical darkening of tattoo ink may occur. This darkening of tattoo ink is dependent on laser wavelength, pulse duration and fluence, with high-energy, nanosecond-pulsed lasers more prone to induce tattoo-ink darkening. Laser toning, consis...

journal_title：Clinical and experimental dermatology

authors： Chung WK,Yang JH,Lee DW,Chang SE,Lee MW,Choi JH,Moon KC

更新日期：2009-12-01 00:00:00

abstract：:Dapsone has potent anti-inflammatory effects, and is used in the treatment of leprosy, cutaneous vasculitis, neutrophilic dermatoses, and dermatitis herpetiformis and other blistering disorders. However, it may cause severe adverse reactions such as hypersensitivity syndrome, which is characterized by fever, skin rash...

journal_title：Clinical and experimental dermatology

authors： Chun JS,Yun SJ,Kim SJ,Lee SC,Won YH,Lee JB

更新日期：2009-12-01 00:00:00

abstract：BACKGROUND:Several studies have shown that in Africa squamous cell carcinoma (SCC) is commoner than other skin malignancies. The risk factors are grouped generally into solar and nonsolar factors and their contributions vary with race, geographical region and site of lesion. This study attempted to identify risk factor...

journal_title：Clinical and experimental dermatology

authors： Asuquo ME,Udosen AM,Ikpeme IA,Ngim NE,Otei OO,Ebughe G,Bassey EE

更新日期：2009-12-01 00:00:00

abstract：BACKGROUND:Momordica charantia (MC; bitter gourd) is a traditional herb commonly used for its antidiabetic, antioxidant, contraceptive and antibacterial properties. It is also used for the rapid healing of wounds. AIM:To observe the topical effect of MC extract on the wound-healing process in rats with diabetes induce...

journal_title：Clinical and experimental dermatology

authors： Teoh SL,Latiff AA,Das S

更新日期：2009-10-01 00:00:00

abstract：:A peculiar observation published in 1971 by Chernosky et al. is revisited in this paper. An African American mother and three of her four children (two girls and one boy) had hyperpigmented skin areas arranged along Blaschko's lines. According to the current knowledge of formal genetics, a mendelian mode of transmissi...

journal_title：Clinical and experimental dermatology

authors： Happle R

更新日期：2009-10-01 00:00:00

abstract：:Asymmetrical periflexural exanthem is a rare clinical condition, seen almost exclusively in children. Very few adult cases have been reported in the literature. We report a case of this rare eruption in an adult man showing characteristic clinical and histological features. Interestingly, this patient also exhibited a...

journal_title：Clinical and experimental dermatology

authors： Dar NR,Raza N

更新日期：2009-10-01 00:00:00

abstract：AIM:To evaluate the effectiveness of a silicone gel in treating surgical wounds compared with a control group of the same phenotype and same scar site for which a placebo was advised. METHODS:This was a randomized controlled trial, carried out in a dermatology department of a university hospital. In total, we studied ...

journal_title：Clinical and experimental dermatology

authors： de Giorgi V,Sestini S,Mannone F,Papi F,Alfaioli B,Gori A,Lotti T

更新日期：2009-08-01 00:00:00

abstract：:Japan is currently experiencing many outbreaks of scabies, occurring mainly in long-term care facilities. Scabies burrows, the only pathognomonic lesion for scabies, often occur on the creases of the palms, and are followed by a pattern of scale reminiscent of the 'wake' left on the surface of water by a moving bird o...

journal_title：Clinical and experimental dermatology

authors： Yoshizumi J,Harada T

更新日期：2009-08-01 00:00:00

abstract：BACKGROUND:Androgenic alopecia is known to be androgen-dependent. Insulin is found in hair follicles and may play a role in the regulation of androgen metabolism and the hair-growth cycle. OBJECTIVES:To compare the insulin resistance between people with androgenic alopecia and a control group. METHODS:A case-control ...

journal_title：Clinical and experimental dermatology

authors： Nabaie L,Kavand S,Robati RM,Sarrafi-Rad N,Kavand S,Shahgholi L,Meshkat-Razavi G

更新日期：2009-08-01 00:00:00

abstract：:Palmoplantar punctate keratoses may be the main cutaneous sign of various diseases (porokeratosis punctata palmaris et plantaris, keratosis punctata of the palmar creases, familial punctate palmoplantar keratoderma) or represent a secondary feature [Cowden's syndrome (CS) and Darier's disease]. In CS, such keratoses u...

journal_title：Clinical and experimental dermatology

authors： Ferran M,Bussaglia E,Matias-Guiu X,Pujol RM

更新日期：2009-07-01 00:00:00

abstract：:A 48-year-old patient presented with a nonhealing leg ulcer and a raised white blood cell count. He was diagnosed with pyoderma gangrenosum (PG) and small lymphocytic leukaemia/chronic lymphocytic leukaemia (SLL/CLL). Eight months later, after undergoing treatment with chlorambucil for the SLL/CLL, and prednisone, cic...

journal_title：Clinical and experimental dermatology

authors： Branagan NM,Higgins SP,Halim SA,Le TH

更新日期：2009-07-01 00:00:00